Adrenal insufficiency exists for both swallowed budesonide and fluticasone propionate in the treatment of eosinophilic esophagitis
نویسندگان
چکیده
منابع مشابه
Adrenal suppression in children treated with swallowed fluticasone and oral viscous budesonide for eosinophilic esophagitis
BACKGROUND Adrenal suppression (AS), a glucocorticoid (GC) side effect associated with significant morbidity, is well described related to inhaled corticosteroid therapy for asthma. Swallowed topical glucocorticoid therapy is the main pharmacotherapy treatment for eosinophilic esophagitis (EoE) and therefore children with EoE are potentially at increased risk of AS. METHODS In this prospectiv...
متن کاملTreatment of eosinophilic esophagitis: is oral viscous budesonide superior to swallowed fluticasone spray?
A 28-year-old man presented with a long history of dysphagia and at least 2 episodes of food impaction. He was a nonsmoker, maintained a very healthy lifestyle, had a history of allergic rhinitis, and had a brother with EoE. An esophagogastroduodenoscopy (EGD) performed in 2007 revealed considerable esophageal trachealization and stenosis, which prevented complete passage of a standard gastrosc...
متن کاملComparative adrenal suppression with inhaled budesonide and fluticasone propionate in adult asthmatic patients.
BACKGROUND A study was performed to compare the adrenal suppression caused by inhaled fluticasone propionate and budesonide on a microgram equivalent basis, each given by metered dose inhaler to asthmatic patients. METHODS Twelve asthmatic patients of mean age 29.9 years, with a forced expiratory volume in one second (FEV1) 92.9% predicted and forced expiratory flow 25-75% (FEF25-75) 69.5% pr...
متن کاملAdrenal suppression with chronic dosing of fluticasone propionate compared with budesonide in adult asthmatic patients.
BACKGROUND In a previous single dosing comparison between fluticasone propionate and budesonide differences in cortisol levels measured at 08.00 hours were observed at doses in excess of 1000 micrograms. The aim of this study was to compare the adrenal suppression caused by chronic twice daily dosing with inhaled fluticasone propionate (FP) and budesonide (B) given on a microgram equivalent bas...
متن کاملBudesonide and fluticasone propionate differentially affect the airway epithelial barrier
BACKGROUND COPD patients have a higher risk of pneumonia when treated with fluticasone propionate (FP) than with placebo, and a lower risk with budesonide (BUD). We hypothesized that BUD and FP differentially affect the mucosal barrier in response to viral infection and/or cigarette smoke. METHODS We assessed protective effects of equivalent concentrations of BUD and FP on cytokine production...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2016
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2016.02.056